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Sphingomyelin Synthase 1 抗体

SGMS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5698483
发货至: 中国
  • 抗原 See all Sphingomyelin Synthase 1 (SGMS1) 抗体
    Sphingomyelin Synthase 1 (SGMS1)
    适用
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    人, 小鼠, 大鼠
    宿主
    • 43
    克隆类型
    • 43
    多克隆
    标记
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    This Sphingomyelin Synthase 1 antibody is un-conjugated
    应用范围
    • 39
    • 20
    • 15
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    • 13
    • 5
    • 4
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    免疫原
    sphingomyelin synthase 1
    亚型
    IgG
    Top Product
    Discover our top product SGMS1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    human heart tissue were subjected to SDS PAGE followed by western blot with FNab07811(SGMS1 antibody) at dilution of 1:300

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    Sphingomyelin Synthase 1 (SGMS1)
    别名
    SGMS1 (SGMS1 产品)
    别名
    MGC81436 antibody, TMEM23 antibody, MOB antibody, MOB1 antibody, SMS1 antibody, hmob33 antibody, 9530058O11Rik antibody, AI841905 antibody, C80702 antibody, Mob antibody, Sms1 antibody, Sor1 antibody, Tmem23 antibody, sphingomyelin synthase 1 antibody, sphingomyelin synthase 1 S homeolog antibody, phosphatidylcholine:ceramide cholinephosphotransferase 1 antibody, SGMS1 antibody, sgms1.S antibody, LOC100013212 antibody, Sgms1 antibody
    背景
    Synonyms:MOB, SMS1, TMEM23 Background:Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
    基因ID
    259230
    UniProt
    Q86VZ5
    途径
    Cellular Response to Molecule of Bacterial Origin
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