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BBS7 抗体

BBS7 适用: 人, 小鼠, 大鼠 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5697175
发货至: 中国
  • 抗原 See all BBS7 抗体
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    适用
    人, 小鼠, 大鼠
    宿主
    • 28
    • 3
    • 1
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    This BBS7 antibody is un-conjugated
    应用范围
    • 26
    • 21
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    免疫原
    Bardet-Biedl syndrome 7
    亚型
    IgG
    Top Product
    Discover our top product BBS7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    别名
    BBS7 (BBS7 产品)
    别名
    BBS7 antibody, bbs2l1 antibody, BBS2L1 antibody, id:ibd5048 antibody, zgc:153772 antibody, 8430406N16Rik antibody, Bardet-Biedl syndrome 7 antibody, bardet-biedl syndrome 7 antibody, Bardet-Biedl syndrome 7 L homeolog antibody, Bardet-Biedl syndrome 7 (human) antibody, BBS7 antibody, bbs7 antibody, MICPUN_100192 antibody, MICPUCDRAFT_16331 antibody, bbs7.L antibody, Bbs7 antibody
    背景
    Synonyms:BBS2L1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
    基因ID
    55212
    UniProt
    Q8IWZ6
    途径
    Hedgehog Signaling
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