BLK 抗体
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- 抗原 See all BLK 抗体
- BLK (B Lymphoid Tyrosine Kinase (BLK))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BLK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 免疫原
- B lymphoid tyrosine kinase
- 亚型
- IgG
- Top Product
- Discover our top product BLK Primary Antibody
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anti-B Lymphoid Tyrosine Kinase (BLK) (AA 241-494) antibody
BLK 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-90) antibodyBLK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7A12 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E5-3A8 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1-00E-06 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9D10B7 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-30), (N-Term) antibodyBLK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03107 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-280) antibodyBLK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 9D10D1 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibodyBLK 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00906(BLK antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- 别名
- BLK (BLK 产品)
- 别名
- bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody
- 背景
- Synonyms: Background:Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor(BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor(BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Specifically binds and phosphorylates CD79A at 'Tyr-188'and 'Tyr-199', as well as CD79B at 'Tyr-196' and 'Tyr-207'. Phosphorylates also the immunoglobulin G receptors FCGR2A, FCGR2B and FCGR2C. With FYN and LYN, plays an essential role in pre-B-cell receptor(pre-BCR)-mediated NF-kappa-B activation. Contributes also to BTK activation by indirectly stimulating BTK intramolecular autophosphorylation. In pancreatic islets, acts as a modulator of beta-cells function through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose.
- 分子量
- 58 kDa
- 基因ID
- 640
- UniProt
- P51451
- 途径
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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