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BLK 抗体

BLK 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 9D10D1 unconjugated
产品编号 ABIN968980
发货至: 中国
  • 抗原 See all BLK 抗体
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    适用
    • 65
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    宿主
    • 53
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    小鼠
    克隆类型
    • 55
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    单克隆
    标记
    • 34
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    This BLK antibody is un-conjugated
    应用范围
    • 52
    • 36
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    • 4
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    ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of BLK expressed in E. coli.
    克隆位点
    9D10D1
    亚型
    IgG2a
    Top Product
    Discover our top product BLK Primary Antibody
  • 应用备注
    ELISA: 1:10000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

  • 抗原
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    别名
    BLK (BLK 产品)
    别名
    bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody
    背景

    Description: BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

    Aliases: MGC10442

    基因ID
    640
    HGNC
    640
    途径
    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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