alpha Actinin 抗体
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- 抗原 See all alpha Actinin (ACTN) 抗体
- alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This alpha Actinin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 免疫原
- actinin, alpha 1
- 亚型
- IgG
- Top Product
- Discover our top product ACTN Primary Antibody
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anti-alpha-Actinin Skeletal Muscle (ACTN) antibody
ACTN 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-Actinin Skeletal Muscle (ACTN) antibodyACTN 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CB11 unconjugated
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- 应用备注
- WB : 1:1000-1:10000 IHC : 1:50-1:500 IF : 1:50-1:500
- 说明
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NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab00322( a-Actinin Antibody) at dilution of 1:2000
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
- 别名
- alpha Actinin (ACTN 产品)
- 别名
- actinin, alpha 4 antibody, alpha-actinin antibody, ACTN4 antibody, ain1 antibody
- 背景
- Synonyms:actinin, alpha 1, ACTN1, alpha Actinin, Alpha actinin 1, F actin cross linking protein, Non muscle alpha actinin 1 Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 103 kDa
- UniProt
- P12814
- 途径
- Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
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