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alpha Actinin 抗体

ACTN 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7073023
发货至: 中国
  • 抗原 See all alpha Actinin (ACTN) 抗体
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    适用
    • 10
    • 8
    • 8
    • 3
    • 1
    人, 小鼠, 大鼠
    宿主
    • 8
    • 2
    克隆类型
    • 8
    • 2
    多克隆
    标记
    • 6
    • 2
    • 2
    This alpha Actinin antibody is un-conjugated
    应用范围
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    小鼠, 大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Human ACTN1
  • 应用备注
    WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1000/1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    别名
    alpha Actinin (ACTN 产品)
    别名
    actinin, alpha 4 antibody, alpha-actinin antibody, ACTN4 antibody, ain1 antibody
    背景
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
    分子量
    103 kDa
    基因ID
    109711
    NCBI登录号
    NP_001093
    UniProt
    P12814
    途径
    Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
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