DC-SIGN/CD209 抗体
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- 抗原 See all DC-SIGN/CD209 (CD209) 抗体
- DC-SIGN/CD209 (CD209) (CD209)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DC-SIGN/CD209 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 品牌
- Picoband™
- 序列
- MSDSKEPRLQ QLGLLEEEQL RGLGFRQTRG YKSLA
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for DC-SIGN detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human,Mouse,Rat.
- 免疫原
- A synthetic peptide corresponding to a sequence of human DC-SIGN (MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLA).
- Top Product
- Discover our top product CD209 Primary Antibody
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anti-CD209 (CD209) (AA 70-404) antibody
CD209 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal C209-1781 unconjugated
anti-CD209 (CD209) (AA 270-404) antibodyCD209 适用: 人 WB, FACS, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 5C2A6 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, IHC (p), IP 宿主: 大鼠 Monoclonal h209 unconjugated
anti-CD209 (CD209) (AA 1-404) antibodyCD209 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD209 (CD209) (AA 115-238) antibodyCD209 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal rC209-1781 unconjugated Recombinant Antibody
anti-CD209 (CD209) (AA 271-380) antibodyCD209 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, ICC 宿主: 小鼠 Monoclonal UW60-1 unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry(Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human
Flow Cytometry, 1-3 μg/1x106 cells, Human - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- DC-SIGN/CD209 (CD209) (CD209)
- 别名
- CD209 (CD209 产品)
- 别名
- CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
- 背景
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Synonyms: CD209 antigen, C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CD209, CD209, CLEC4L
Tissue Specificity: Predominantly expressed in dendritic cells and in DC-residing tissues. Also found in placental macrophages, endothelial cells of placental vascular channels, peripheral blood mononuclear cells, and THP-1 monocytes.
Background: DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) also known as CD209 (Cluster of Differentiation 209) is a protein which in humans is encoded by the CD209 gene. This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene. DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.
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