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DC-SIGN/CD209 抗体 (AA 270-404)

CD209 适用: 人 WB, FACS, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 5C2A6 unconjugated
产品编号 ABIN5611274
发货至: 中国
  • 抗原 See all DC-SIGN/CD209 (CD209) 抗体
    DC-SIGN/CD209 (CD209) (CD209)
    抗原表位
    • 8
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    • 4
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    • 1
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    AA 270-404
    适用
    • 98
    • 29
    • 24
    • 1
    • 1
    宿主
    • 76
    • 38
    • 2
    • 1
    小鼠
    克隆类型
    • 75
    • 42
    单克隆
    标记
    • 57
    • 9
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DC-SIGN/CD209 antibody is un-conjugated
    应用范围
    • 73
    • 41
    • 32
    • 31
    • 25
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD209 (AA: extra 270-404) expressed in E. coli.
    克隆位点
    5C2A6
    亚型
    IgG1
    Top Product
    Discover our top product CD209 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    DC-SIGN/CD209 (CD209) (CD209)
    别名
    CD209 (CD209 产品)
    别名
    CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
    背景

    Description: This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332, often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.

    Aliases: CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1

    分子量
    45.8 kDa
    基因ID
    30835
    HGNC
    30835
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