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Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) 抗体

SCD1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5690340
发货至: 中国
  • 抗原 See all Stearoyl-Coenzyme A Desaturase 1 (SCD1) 抗体
    Stearoyl-Coenzyme A Desaturase 1 (SCD1)
    抗原表位
    • 1
    • 1
    • 1
    AA 21-33
    适用
    • 2
    • 1
    小鼠
    宿主
    • 2
    • 1
    克隆类型
    • 3
    多克隆
    标记
    • 3
    非结合性
    应用范围
    Western Blotting (WB), ELISA
    特异性
    Recognizes mouse SCD1. Detects a band of ~41  kDa by Western Blot.
    免疫原
    Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.
    Top Product
    Discover our top product SCD1 Primary Antibody
  • 应用备注
    ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL, suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk, suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. 0.2um-filtered solution in PBS,  pH 7.4. Contains no preservatives.
    储存液
    Without preservative
    储存条件
    -20 °C
    储存方法
    Stable for at least 6 months after receipt when stored at -20°C.
  • 抗原
    Stearoyl-Coenzyme A Desaturase 1 (SCD1)
    别名
    Stearoyl-CoA Desaturase-1 (SCD1 产品)
    别名
    AA589638 antibody, AI265570 antibody, Scd antibody, Scd-1 antibody, ab antibody, stearoyl-Coenzyme A desaturase 1 antibody, Scd1 antibody
    背景
    Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.
    基因ID
    20249
    UniProt
    P13516
    途径
    Brown Fat Cell Differentiation
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