Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) 抗体
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Quick Overview for Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) 抗体 (ABIN1169094)
抗原
See all Stearoyl-Coenzyme A Desaturase 1 (SCD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-33
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原理
- anti-Stearoyl-CoA Desaturase-1 (mouse), pAb
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特异性
- Recognizes mouse SCD1. Detects a band of ~41 kDa by Western Blot.
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产品特性
- Polyclonal Antibody. Recognizes mouse SCD1. Detects a band of ~41 kDa by Western Blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.
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过滤
- 0.2 μm filtered
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免疫原
- Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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有效期
- 6 months
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- Stearoyl-Coenzyme A Desaturase 1 (SCD1)
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别名
- Stearoyl-CoA Desaturase-1
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背景
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Alternate Names/Synonyms: SCD1, Acyl-CoA Desaturase 1, Fatty Acid Desaturase 1
Product Description: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.
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UniProt
- P13516
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途径
- Brown Fat Cell Differentiation
抗原
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