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PTPN5 抗体 (AA 180-230)

PTPN5 适用: 人, 小鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5690111
发货至: 中国
  • 抗原 See all PTPN5 抗体
    PTPN5 (Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5))
    抗原表位
    • 15
    • 12
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 180-230
    适用
    • 53
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 50
    • 5
    克隆类型
    • 51
    • 4
    多克隆
    标记
    • 22
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPN5 antibody is un-conjugated
    应用范围
    • 50
    • 28
    • 13
    • 13
    • 11
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    PTPN5 antibody is human and mouse reactive.
    纯化方法
    PTPN5 antibody is affinity chromatography purified via peptide column.
    免疫原
    PTPN5 antibody was raised against an 18 amino acid peptide near the amino terminus of human PTPN5.

    The immunogen is located within amino acids 180 - 230 of PTPN5.
    亚型
    IgG
    Top Product
    Discover our top product PTPN5 Primary Antibody
  • 应用备注
    PTPN5 antibody can be used for detection of PTPN5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PTPN5 antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    PTPN5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    PTPN5 (Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5))
    别名
    PTPN5 (PTPN5 产品)
    别名
    STEP antibody, Step antibody, PTPSTEP antibody, protein tyrosine phosphatase, non-receptor type 5 antibody, ptpn5 antibody, PTPN5 antibody, Ptpn5 antibody
    背景
    The protein tyrosine phosphatase PTPN5, also known as Striatal enriched phosphatase (STEP), is involved in the regulation of synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (1). It is expressed in dopaminoceptive neurons of the central nervous system and multiple forms of PTPN5 show differential enrichment in adult brain regions (2). NMDA-mediated activation of PTPN5 is an important mechanism for regulation of Erk activity in neurons (3). Furthermore, PTPN5 is involved in the regulation of both NMDAR and AMPAR trafficking (4,5). PTPN5 may play a role in Alzheimer's disease (1).
    分子量
    Predicted: 62 kDa

    Observed: 60 kDa
    基因ID
    84867
    NCBI登录号
    NP_008837
    UniProt
    Q86TL6
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