HES5 抗体 (N-Term)
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- 抗原 See all HES5 抗体
- HES5 (Hairy and Enhancer of Split 5 (HES5))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HES5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- HES5 antibody is human, mouse and rat reactive. At least two isoforms of HES5 are known to exist, this antibody will detect both isoforms.
- 纯化方法
- HES5 antibody is affinity chromatography purified via peptide column.
- 免疫原
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HES5 antibody was raised against a 19 amino acid peptide near the amino terminus of human HES5.
The immunogen is located within the first 50 amino acids of HES5. - 亚型
- IgG
- Top Product
- Discover our top product HES5 Primary Antibody
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anti-Hairy and Enhancer of Split 5 (HES5) antibody
HES5 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 21-120) antibodyHES5 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 1-50) antibodyHES5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 83-95) antibodyHES5 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴 WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 1-166) antibodyHES5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 81-115) antibodyHES5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51477 unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (C-Term) antibodyHES5 适用: 人, 小鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 28-121) antibodyHES5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 28-121) antibodyHES5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) antibodyHES5 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- HES5 antibody can be used for detection of HES5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- HES5 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- HES5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- HES5 (Hairy and Enhancer of Split 5 (HES5))
- 别名
- HES5 (HES5 产品)
- 别名
- fk51a02 antibody, her15 antibody, hes5 antibody, wu:fk51a02 antibody, zgc:136520 antibody, bHLHb38 antibody, hairy and enhancer of split-related 15, tandem duplicate 1 antibody, hes family bHLH transcription factor 5 antibody, hairy and enhancer of split 5 (Drosophila) antibody, transcription factor HES-5-like antibody, her15.1 antibody, HES5 antibody, hes5 antibody, LOC100221262 antibody, LOC100226434 antibody, Hes5 antibody
- 背景
- HES5 is a member of the HES family of transcriptional repressors, which are the mammalian homologs of the Drosophila Hairy and Enhancer of Split and contain basic Helix-loop-helix (bHLH) and Orange domains (1). The HES5 gene is a downstream target of the Notch signaling pathway and its expression is downregulated during human cartilage differentiation (2). HES5 can directly repress transcription of the E3 ligase FBW7-beta, creating a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions (3).
- 分子量
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Predicted: 18 kDa
Observed: 17 kDa - 基因ID
- 388585
- NCBI登录号
- NP_001010926
- UniProt
- Q5TA89
- 途径
- Stem Cell Maintenance, Tube Formation
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