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FGFR3 抗体 (AA 630-680)
FGFR3
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
FGFR3抗体详情
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抗原
See all FGFR3 抗体
FGFR3
(Fibroblast Growth Factor Receptor 3 (FGFR3))
抗原表位
All epitopes for FGFR3 抗体
AA 630-680
适用
All reactivities for FGFR3 抗体
人, 小鼠, 大鼠
宿主
All hosts for FGFR3 抗体
兔
克隆类型
All clonalities for FGFR3 抗体
多克隆
标记
All conjugates for FGFR3 抗体
This FGFR3 antibody is un-conjugated
应用范围
All applications for FGFR3 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
特异性
FGFR3 antibody is human, mouse and rat reactive. At least three isoforms of FGFR3 are known to exist, this antibody will detect all three.
纯化方法
FGFR3 Antibody is affinity chromatography purified via peptide column.
免疫原
FGFR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FGFR3. The immunogen is located within amino acids 630 - 680 of FGFR3.
亚型
IgG
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Discover our top product FGFR3 Primary Antibody
Alternatives
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使用细节
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应用备注
FGF3 antibody can be used for detection of FGFR3 by Western blot at 1 - 2 μ,g/mL.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
FGFR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
FGFR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
FGFR3目标详情
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抗原
FGFR3
(Fibroblast Growth Factor Receptor 3 (FGFR3))
别名
FGFR3 (FGFR3 产品 )
别名
FGFR3 antibody, LOC100034114 antibody, ACH antibody, CD333 antibody, CEK2 antibody, HSFGFR3EX antibody, JTK4 antibody, FR3 antibody, Fgfr-3 antibody, Flg-2 antibody, HBGFR antibody, Mfr3 antibody, sam3 antibody, fc27h01 antibody, wu:fc27h01 antibody, fibroblast growth factor receptor 3 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antibody, FGFR3 antibody, fgfr3.S antibody, Fgfr3 antibody, fgfr3 antibody
背景
FGFR3 Antibody: FGFR3 is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis (1). It is required for normal skeleton development and promotes apoptosis in chondrocytes and cancer cell proliferation. FGFR3 protein contains three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain (1,2). It is alternatively spliced to produce three isoforms that are expressed in brain, kidney and testis. Defects in FGFR3 are associated with several diseases, including achondroplasia and hypochondroplasia (3,4). Mutations in FGFR3 are also a cause of some bladder and cervical cancers (5).
分子量
Predicted: 89 kDa Observed: 9+2, 98 kDa
基因ID
2261
NCBI登录号
NP_001156685
UniProt
P22607
途径
RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Stem Cell Maintenance , Growth Factor Binding
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