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ATG4C 抗体 (C-Term)

ATG4C 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5689885
发货至: 中国
  • 抗原 See all ATG4C 抗体
    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
    抗原表位
    • 15
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 54
    • 30
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 48
    • 10
    • 2
    • 1
    克隆类型
    • 53
    • 8
    多克隆
    标记
    • 27
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG4C antibody is un-conjugated
    应用范围
    • 55
    • 22
    • 18
    • 13
    • 13
    • 13
    • 13
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    ATG4C antibody is human, mouse and rat reactive. ATG4C is predicted to not cross-react with other ATG4 proteins.
    纯化方法
    ATG4C antibody is affinity chromatography purified via peptide column.
    免疫原
    ATG4C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ATG4C.

    The immunogen is located within the last 50 amino acids of ATG4C.
    亚型
    IgG
    Top Product
    Discover our top product ATG4C Primary Antibody
  • 应用备注
    ATG4C antibody can be used for detection of ATG4C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ATG4C antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    ATG4C antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
    别名
    ATG4C (ATG4C 产品)
    别名
    apg4c antibody, atg4cl antibody, zgc:86888 antibody, wu:fc56g07 antibody, APG4-C antibody, APG4C antibody, AUTL1 antibody, AUTL3 antibody, Apg4-C antibody, Apg4c antibody, Atg4cl antibody, Autl1 antibody, autophagy related 4C cysteine peptidase antibody, autophagy related 4C, cysteine peptidase antibody, cysteine protease ATG4C antibody, ATG4C antibody, atg4c antibody, Tsp_15996 antibody, Atg4c antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4C, also known as autophagin-3, is one of four mammalian orthologs of the yeast ATG4 protein, all four are cysteine proteases (3). Recent studies have shown that ATG4C and Beclin-1 are regulated by the microRNA miR-376b, overexpression of miR-376b led to decreased mRNA and protein levels, thereby blocking starvation and TOR inhibition-related autophagy (4).
    分子量
    Predicted: 50 kDa

    Observed: 57 kDa
    基因ID
    84938
    NCBI登录号
    NP_835739
    UniProt
    Q96DT6
    途径
    Autophagy
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