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PRKAA1 抗体 (AA 485-489)
PRKAA1
适用: 人, 小鼠, 大鼠
WB, IHC
宿主: 兔
Polyclonal
unconjugated
PRKAA1抗体详情
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抗原
See all PRKAA1 抗体
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
抗原表位
All epitopes for PRKAA1 抗体
AA 485-489
适用
All reactivities for PRKAA1 抗体
人, 小鼠, 大鼠
宿主
All hosts for PRKAA1 抗体
兔
克隆类型
All clonalities for PRKAA1 抗体
多克隆
标记
All conjugates for PRKAA1 抗体
This PRKAA1 antibody is un-conjugated
应用范围
All applications for PRKAA1 抗体
Western Blotting (WB), Immunohistochemistry (IHC)
特异性
This antibody detects endogenous level of total AMPKα,1 protein.
纯化方法
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
免疫原
AMPKa1 (Ab-487) antibody was raised in was raised against a peptide sequence around aa.485~489 (S-G-S-V-S) derived from Human AMPKα,1.
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使用细节
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应用备注
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store antibody at -20°C for up to one year.
PRKAA1目标详情
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抗原
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
别名
AMPKa1 (PRKAA1 产品 )
别名
AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
背景
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
分子量
63 kDa
基因ID
5562
NCBI登录号
NP_006242
UniProt
Q13131 , P54646
途径
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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