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PRKAA1 抗体 (AA 1-300)

This 兔多克隆 antibody specifically detects PRKAA1 in WB 和 IF. It exhibits reactivity toward 人. It has been mentioned in 3+ publications

Immunohistochemistry of paraffin-embedded Human gastric using PRKAA1 antibody at dilution of 1:100 (x400 lens). (PRKAA1 抗体 (AA 1-300))

IHC

Immunohistochemistry (IHC) image for anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 1-300) antibody (ABIN3021788) (PRKAA1 抗体 (AA 1-300))

IHC

Western Blotting (WB) image for anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 1-300) antibody (ABIN3021788) (PRKAA1 抗体 (AA 1-300))

Active AMPK antagonized PRRSV infection. (PRKAA1 抗体 (AA 1-300))

13 images

(3 references)

产品编号 ABIN3021788

发货至: 中国

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Quick Overview for PRKAA1 抗体 (AA 1-300) (ABIN3021788)

抗原

See all PRKAA1 抗体

PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PRKAA1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF)

抗原表位
53

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AA 1-300

序列

MRRLSSWRKM ATAEKQKHDG RVKIGHYILG DTLGVGTFGK VKVGKHELTG HKVAVKILNR QKIRSLDVVG KIRREIQNLK LFRHPHIIKL YQVISTPSDI FMVMEYVSGG ELFDYICKNG RLDEKESRRL FQQILSGVDY CHRHMVVHRD LKPENVLLDA HMNAKIADFG LSNMMSDGEF LRTSCGSPNY AAPEVISGRL YAGPEVDIWS SGVILYALLC GTLPFDDDHV PTLFKKICDG IFYTPQYLNP SVISLLKHML QVDPMKRATI KDIREHEWFK QDLPKYLFPE DPSYSSTMID

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AMPKalpha1 alpha 1 (NP_006242.5).

亚型

IgG
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 28-257) antibody
PRKAA1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (pThr172), (pThr183) antibody
PRKAA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) antibody
PRKAA1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2B7 unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 351-450) antibody
PRKAA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 351-450) antibody
PRKAA1 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) antibody
KD Validated PRKAA1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2685 unconjugated Recombinant Antibody

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 451-550) antibody
PRKAA1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D8 unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 325-543), (Catalytic Subunit) antibody
PRKAA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (pSer487) antibody
PRKAA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (pSer486) antibody
PRKAA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Xiong, Zhang, Zhao, Zhao, Chen, Mei: "Antidiabetic activities of entagenic acid in type 2 diabetic db/db mice and L6 myotubes via AMPK/GLUT4 pathway." in: Journal of ethnopharmacology, Vol. 211, pp. 366-374, (2018) (PubMed).

Yan, Du, Li, Chen, Yan, Chen, Hu, Chang: "CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo." in: Urologic oncology, Vol. 36, Issue 6, pp. 312.e1-312.e8, (2018) (PubMed).

Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).
抗原

PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

别名

PRKAA1

背景

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.,PRKAA1,AMPK,AMPKa1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Lipid Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Hypoxia,Lipids,Fatty Acids,Regulator of mTOR complex function,Regulators,PRKAA1

分子量

64 kDa/65 kDa

基因ID

5562

UniProt

Q13131

途径

AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect