PAK1 抗体 (pThr402)
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Quick Overview for PAK1 抗体 (pThr402) (ABIN5688931)
抗原
See all PAK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr402
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纯化方法
- Affinity Purified
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr402 of rat p21 activated kinase 2 (PAK-2). The peptide sequence used is identical in PAK-1, 2 and 3. Note: Thr402 in PAK-2 corresponds to Thr423 in human PAK-1.
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anti-P21-Activated Kinase 1 (PAK1) (AA 191-280) antibody
PAK1 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-P21-Activated Kinase 1 (PAK1) (Center) antibodyPAK1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 252-501) antibodyPAK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 1-240) antibodyPAK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibodyPAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 401-430) antibodyPAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (Ser204) antibodyPAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (Thr402), (Thr421), (Thr423) antibodyPAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (N-Term) antibodyPAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 245-490) antibodyPAK1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, human and mouse based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- PAK1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- PAK1 (P21-Activated Kinase 1 (PAK1))
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别名
- PAK1
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背景
- In mammals, there are several identified isoforms of p21-activated protein kinases or PAKs: alpha-PAK (also known as PAK-1) and beta-PAK (also known as PAK-3) are mostly brain-specific, while -PAK (also known as PAK-2) is expressed ubiquitously (Jakobi et al., 2003). Mutations of the gene coding for PAK-3 are associated with X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004). PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death (Jakobi et al., 2003, Walter et al., 1998). Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK (Jakobi et al., 2000).
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分子量
- 68/70 kDa
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基因ID
- 29431
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UniProt
- P35465
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途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
抗原
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