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PAK1 抗体 (pThr402)

This anti-PAK1 antibody is a 兔多克隆 antibody detecting PAK1 in WB. Suitable for 人, 大鼠, 小鼠, Cow 和犬.

产品编号 ABIN5688931

发货至: 中国

Quick Overview for PAK1 抗体 (pThr402) (ABIN5688931)

抗原

See all PAK1 抗体

PAK1 (P21-Activated Kinase 1 (PAK1))

适用

173
91
79
6
5
4
4
4
3
2
1
1

人, 大鼠, 小鼠, Cow, 犬

宿主

兔

克隆类型

多克隆

标记

91
8
6
6
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3

This PAK1 antibody is un-conjugated

应用范围

112
62
47
39
39
34
30
13
11
10
9
4
3
3
2
1

Western Blotting (WB)

Discover our top product PAK1 Primary Antibody

抗原表位
28

22

15

13

11

9

8

8

7

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr402

纯化方法

Affinity Purified

免疫原

Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr402 of rat p21 activated kinase 2 (PAK-2). The peptide sequence used is identical in PAK-1, 2 and 3. Note: Thr402 in PAK-2 corresponds to Thr423 in human PAK-1.
anti-P21-Activated Kinase 1 (PAK1) (AA 191-280) antibody
PAK1 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 4D1 unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Center) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 252-501) antibody
PAK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 1-240) antibody
PAK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 401-430) antibody
PAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Ser204) antibody
PAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 245-490) antibody
PAK1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (N-Term) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (pThr423) antibody
PAK1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB11381 unconjugated

应用备注

The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, human and mouse based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

限制

仅限研究用
状态

Liquid

缓冲液

100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

储存条件

-20 °C

储存方法

PAK1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
抗原

PAK1 (P21-Activated Kinase 1 (PAK1))

别名

PAK1

背景

In mammals, there are several identified isoforms of p21-activated protein kinases or PAKs: alpha-PAK (also known as PAK-1) and beta-PAK (also known as PAK-3) are mostly brain-specific, while -PAK (also known as PAK-2) is expressed ubiquitously (Jakobi et al., 2003). Mutations of the gene coding for PAK-3 are associated with X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004). PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death (Jakobi et al., 2003, Walter et al., 1998). Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK (Jakobi et al., 2000).

分子量

68/70 kDa

基因ID

29431

UniProt

P35465

途径

MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis

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