PTPRM 抗体 (AA 565-742)
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- 抗原 See all PTPRM 抗体
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
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抗原表位
- AA 565-742
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PTPRM antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human PTPRM (AA: extra 565-742) expressed in E. coli.
- 克隆位点
- 8F1C10
- 亚型
- IgG1
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
- 别名
- PTPRM (PTPRM 产品)
- 别名
- cb984 antibody, ptprm antibody, zgc:110218 antibody, PTPRM antibody, p-ptp-mu antibody, ptprl1 antibody, r-ptpu antibody, rptpm antibody, rptpu antibody, PTPRL1 antibody, R-PTP-MU antibody, RPTPM antibody, RPTPU antibody, hR-PTPu antibody, RPTPmu antibody, mKIAA4044 antibody, protein tyrosine phosphatase, receptor type, M, a antibody, protein tyrosine phosphatase, receptor type M antibody, protein tyrosine phosphatase, receptor type, M, b antibody, receptor-type tyrosine-protein phosphatase mu antibody, protein tyrosine phosphatase, receptor type, M antibody, ptprma antibody, PTPRM antibody, ptprmb antibody, ptprm antibody, LOC100550127 antibody, LOC100564083 antibody, Ptprm antibody
- 背景
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Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Aliases: RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU
- 分子量
- 163.7 kDa
- 基因ID
- 5797
- HGNC
- 2215
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