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Recombinant TNFRSF8 抗体

TNFRSF8 适用: 人 FACS, IHC, IF, ELISA, InhA 宿主: 兔 Chimeric Ki-4 unconjugated Recombinant Antibody
产品编号 ABIN5668113
发货至: 中国
  • 抗原 See all TNFRSF8 抗体
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    抗体类型
    Recombinant Antibody
    适用
    • 131
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    宿主
    • 86
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    克隆类型
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    Chimeric
    标记
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    This TNFRSF8 antibody is un-conjugated
    应用范围
    • 99
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Inhibition Assay (InhA)
    特异性
    The antibody binds to CD30.
    产品特性

    OriginalSpeciesName: Mouse

    OriginalFormat: IgG1

    纯化方法
    Purified antibody.
    免疫原
    Human CD30.
    克隆位点
    Ki-4
    亚型
    IgG kappa
    Top Product
    Discover our top product TNFRSF8 Primary Antibody
  • 应用备注
    The antibody binds specifically to CD30, a cell membrane protein which belongs to the tumour necrosis factor receptor family. Incubation of CD30 positive L540 cells with Ki-4 antibody completely inhibits release of soluble CD30 (in contrast to Ki-3, Ab00474). CD30 is expressed on activated lymphocytes, and binding by its ligands TRAF2 and TRAF5 results in the activation of NF-kappaB, thereby regulating gene expression. CD30 is also associated with Hodgkin Lymphoma, and its expression acts as a tumour marker. Targeting the CD30 antigen with specific monoclonal antibodies is a possible therapy for Hodgkin's lymphoma.
    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    别名
    CD30 (TNFRSF8 产品)
    别名
    CD30 antibody, D1S166E antibody, Ki-1 antibody, Cd30 antibody, Ki antibody, TNFRSF8 antibody, TNF receptor superfamily member 8 antibody, tumor necrosis factor receptor superfamily, member 8 antibody, TNFRSF8 antibody, Tnfrsf8 antibody
    背景
    TNFRSF8, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30
    UniProt
    P28908
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