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Recombinant p53 抗体 (AA 371-380)

This anti-p53 antibody is a 兔 Chimeric antibody detecting p53 in WB, ELISA, IF, IHC (p), IP, IHC (fro) 和 in vivo. Suitable for 人, 小鼠, 大鼠, 猴 和 兔.
产品编号 ABIN5668086
发货至: 中国

Quick Overview for Recombinant p53 抗体 (AA 371-380) (ABIN5668086)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠, 猴, 兔

宿主

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克隆类型

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Chimeric

标记

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This p53 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)

克隆位点

PAb421
  • 抗原表位

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    AA 371-380

    原理

    Anti-p53 [PAb421], Rabbit IgG, kappa

    特异性

    Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".

    交叉反应

    猴, 小鼠, 兔, 大鼠

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    Synthetic peptide corresponding to aa 371-380 of human p53.

    亚型

    IgG kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53

    背景

    Tumor suppressor p53, Cellular tumor antigen p53

    UniProt

    P04637

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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