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Recombinant p53 抗体 (AA 371-380)

This anti-p53 antibody is a 小鼠 单克隆 antibody detecting p53 in WB, ELISA, IF, IHC (p), IP, IHC (fro) 和 in vivo. Suitable for 人, 小鼠, 大鼠, 猴 和 兔.
产品编号 ABIN5668085
发货至: 中国

Quick Overview for Recombinant p53 抗体 (AA 371-380) (ABIN5668085)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠, 猴, 兔

宿主

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小鼠

克隆类型

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单克隆

标记

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This p53 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)

克隆位点

PAb421
  • 抗原表位

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    AA 371-380

    原理

    Anti-p53 [PAb421], Mouse IgG2a, kappa

    特异性

    Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".

    交叉反应

    猴, 小鼠, 兔, 大鼠

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    Synthetic peptide corresponding to aa 371-380 of human p53.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53

    背景

    Tumor suppressor p53, Cellular tumor antigen p53

    UniProt

    P04637

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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