Recombinant p53 抗体 (AA 371-380)
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- 抗原 See all p53 (TP53) 抗体
- p53 (TP53) (Tumor Protein P53 (TP53))
- 抗体类型
- Recombinant Antibody
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抗原表位
- AA 371-380
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适用
- 人, 小鼠, 大鼠, 猴, 兔
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This p53 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)
- 原理
- Anti-p53 [PAb421], Mouse IgG2a, kappa
- 特异性
- Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".
- 交叉反应
- 猴, 小鼠, 兔, 大鼠
- 产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
- 纯化方法
- Protein A affinity purified
- 免疫原
- Synthetic peptide corresponding to aa 371-380 of human p53.
- 克隆位点
- PAb421
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product TP53 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- 抗原
- p53 (TP53) (Tumor Protein P53 (TP53))
- 别名
- p53 (TP53 产品)
- 背景
- Tumor suppressor p53, Cellular tumor antigen p53
- UniProt
- P04637
- 途径
- p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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