FGFR1 抗体 (AA 489-520)
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Quick Overview for FGFR1 抗体 (AA 489-520) (ABIN5647574)
抗原
See all FGFR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 489-520
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 489-520 (FGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDA-human) were used as the immunogen for the FGFR1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the FGFR1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the FGFR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
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别名
- FGFR1 / Fibroblast growth factor receptor 1
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背景
- FGFR1, Fibroblast growth factor receptor 1, also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. The FGFR1 gene is localized to 8p12-p11.2 by in situ hybridization. FGFR1 is essential for the normal formation of the organ of Corti and that phenotype severity observed in FGFR1 mutants is dependent on the dose of FGFR1. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome 2.
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UniProt
- P11362
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
抗原
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