LBP 抗体 (AA 26-257)
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Quick Overview for LBP 抗体 (AA 26-257) (ABIN5647187)
抗原
See all LBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-257
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原理
- LBP Antibody
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纯化方法
- Antigen affinity
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免疫原
- A recombinant human protein corresponding to amino acids A26-R257 was used as the immunogen for the LBP antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LBP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LBP (Lipopolysaccharide Binding Protein (LBP))
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别名
- LBP
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背景
- Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
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UniProt
- P18428
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
抗原
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