电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

LBP 抗体

LBP 适用: 小鼠 ELISA 宿主: 小鼠 Monoclonal biG35 unconjugated
产品编号 ABIN343174
发货至: 中国
  • 抗原 See all LBP 抗体
    LBP (Lipopolysaccharide Binding Protein (LBP))
    适用
    • 39
    • 19
    • 17
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    小鼠
    宿主
    • 45
    • 18
    • 5
    • 2
    小鼠
    克隆类型
    • 47
    • 23
    单克隆
    标记
    • 56
    • 7
    • 3
    • 3
    • 1
    This LBP antibody is un-conjugated
    应用范围
    • 47
    • 27
    • 24
    • 17
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    特异性
    Mouse LBP. The antibody don't blocks LPS binding to membrane bound CD14.
    交叉反应
    大鼠
    纯化方法
    Protein A affinity column
    免疫原
    native mouse LBP
    克隆位点
    BiG35
    亚型
    IgG2a
    Top Product
    Discover our top product LBP Primary Antibody
  • 应用备注
    ELISA, LBP inhibition studies, Western Blot. Non inhibition of LPS binding to membrane bound CD14, Binding titre at - ELISA: more than1:20.000
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with bidistilled water
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.18
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
  • Stamme, Mueller, Hamann, Gutsmann, Seydel: "Surfactant protein a inhibits lipopolysaccharide-induced immune cell activation by preventing the interaction of lipopolysaccharide with lipopolysaccharide-binding protein." in: American journal of respiratory cell and molecular biology, Vol. 27, Issue 3, pp. 353-60, (2002) (PubMed).

    Gutsmann, Mueller, Carroll, MacKenzie, Wiese, Seydel: "Dual role of lipopolysaccharide (LPS)-binding protein in neutralization of LPS and enhancement of LPS-induced activation of mononuclear cells." in: Infection and immunity, Vol. 69, Issue 11, pp. 6942-50, (2001) (PubMed).

    Hamann, Schumann, Flad, Brade, Rietschel, Ulmer: "Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation." in: European journal of immunology, Vol. 30, Issue 1, pp. 211-6, (2000) (PubMed).

  • 抗原
    LBP (Lipopolysaccharide Binding Protein (LBP))
    别名
    Lipopolysaccharide (LPS)-Binding Protein (LBP) (LBP 产品)
    别名
    BPIFD2 antibody, Bpifd2 antibody, Ly88 antibody, LPSBP antibody, LBP antibody, lipopolysaccharide binding protein antibody, lipopolysaccharide-binding protein antibody, LBP antibody, Lbp antibody, LOC100472839 antibody
    背景
    Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
    分子量
    ~58kDa
    基因ID
    16803
    UniProt
    Q61805
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
You are here:
客服