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AGR2 抗体 (AA 1-175)

This anti-AGR2 antibody is a 小鼠 单克隆 antibody detecting AGR2 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 9+ publications.
产品编号 ABIN564604
发货至: 中国

Quick Overview for AGR2 抗体 (AA 1-175) (ABIN564604)

抗原

See all AGR2 抗体
AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

适用

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  • 39
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  • 2
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  • 1
  • 1

宿主

  • 84
  • 27
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 78
  • 35
单克隆

标记

  • 66
  • 14
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
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  • 1
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This AGR2 antibody is un-conjugated

应用范围

  • 90
  • 60
  • 37
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  • 28
  • 20
  • 14
  • 14
  • 14
  • 5
  • 4
  • 4
  • 2
Western Blotting (WB), ELISA

克隆位点

1C3
  • 抗原表位

    • 28
    • 15
    • 6
    • 5
    • 5
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    • 2
    • 1
    • 1
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    • 1
    AA 1-175

    原理

    Mouse monoclonal antibody raised against a full length recombinant AGR2.

    序列

    MEKIPVSAFL LLVALSYTLA RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    AGR2 (AAH15503.1, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Dong, Wodziak, Lowe: "Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface." in: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8016-27, (2015) (PubMed).

    Riener, Thiesler, Hellerbrand, Amann, Cathomas, Fritzsche, Dahl, Bahra, Weichert, Terracciano, Kristiansen: "Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas." in: European journal of cancer (Oxford, England : 1990), Vol. 50, Issue 10, pp. 1722-30, (2014) (PubMed).

    Gray, Murray, Nowicki, Remnant, Scherl, Muller, Vojtesek, Hupp: "Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein." in: Protein science : a publication of the Protein Society, Vol. 22, Issue 9, pp. 1266-78, (2013) (PubMed).

    Wayner, Quek, Ahmad, Ho, Loprieno, Zhou, Ellis, True, Liu: "Development of an ELISA to detect the secreted prostate cancer biomarker AGR2 in voided urine." in: The Prostate, Vol. 72, Issue 9, pp. 1023-34, (2012) (PubMed).

    Darb-Esfahani, Fritzsche, Kristiansen, Weichert, Sehouli, Braicu, Dietel, Denkert: "Anterior gradient protein 2 (AGR2) is an independent prognostic factor in ovarian high-grade serous carcinoma." in: Virchows Archiv : an international journal of pathology, Vol. 461, Issue 2, pp. 109-16, (2012) (PubMed).

    Lepreux, Bioulac-Sage, Chevet: "Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 31, Issue 3, pp. 322-8, (2011) (PubMed).

    Ambolet-Camoit, Bui, Pierre, Chevallier, Marchand, Coumoul, Garlatti, Andreau, Barouki, Aggerbeck: "2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 2, pp. 501-12, (2010) (PubMed).

    Maslon, Hrstka, Vojtesek, Hupp: "A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin." in: Journal of molecular biology, Vol. 404, Issue 3, pp. 418-38, (2010) (PubMed).

    Zhao, Lee, Brown, Molloy, Marx, Pavlakis, Boyer, Stockler, Kaplan, Breit, Sutherland, Henshall, Horvath: "Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling." in: Cancer research, Vol. 69, Issue 19, pp. 7696-703, (2009) (PubMed).

  • 抗原

    AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

    别名

    AGR2

    背景

    Full Gene Name: anterior gradient homolog 2 (Xenopus laevis)
    Synonyms: AG2,GOB-4,HAG-2,XAG-2

    基因ID

    10551
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