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SQSTM1 抗体 (AA 1-440)

Name: SQSTM1 抗体 (AA 1-440)
SKU: ABIN563860
Availability: OutOfStock

This anti-SQSTM1 antibody is a 小鼠单克隆 antibody detecting SQSTM1 in WB, ELISA 和 IF. Suitable for 人. This Primary Antibody has been cited in 88+ publications.

Western Blot detection against Immunogen (74. (SQSTM1 抗体 (AA 1-440))

Immunofluorescence of monoclonal antibody to SQSTM1 on HeLa cell. (SQSTM1 抗体 (AA 1-440))

Detection limit for recombinant GST tagged SQSTM1 is approximately 0. (SQSTM1 抗体 (AA 1-440))

ELISA

3 images

(88 references)

产品编号 ABIN563860

发货至: 中国

Quick Overview for SQSTM1 抗体 (AA 1-440) (ABIN563860)

抗原

See all SQSTM1 抗体

SQSTM1 (Sequestosome 1 (SQSTM1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This SQSTM1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

2C11

Discover our top product SQSTM1 Primary Antibody

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AA 1-440

原理

Mouse monoclonal antibody raised against a full length recombinant SQSTM1.

序列

MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL

交叉反应

人, 小鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Sequestosome 1 (SQSTM1) antibody
KO Validated SQSTM1 适用: 人 WB, IF, IP, ICC, FACS, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 51-150) antibody
SQSTM1 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibody
SQSTM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 232-356) antibody
SQSTM1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5H7E2 unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 317-346) antibody
SQSTM1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4614 unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 136-400) antibody
SQSTM1 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (C-Term) antibody
SQSTM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) antibody
SQSTM1 适用: 人, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 5A2 unconjugated

anti-Sequestosome 1 (SQSTM1) antibody
KO Validated SQSTM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 69-96), (N-Term) antibody
SQSTM1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Korwitz, Merkwirth, Richter-Dennerlein, Tröder, Sprenger, Quirós, López-Otín, Rugarli, Langer: "Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria." in: The Journal of cell biology, Vol. 212, Issue 2, pp. 157-66, (2016) (PubMed).

Sydow, Hochgräfe, Könen, Cadinu, Matenia, Petrova, Joseph, Dennissen, Mandelkow: "Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD." in: Acta neuropathologica communications, Vol. 4, pp. 17, (2016) (PubMed).

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Aydinlik, Erkisa, Cevatemre, Sarimahmut, Dere, Ari, Ulukaya: "Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 49-57, (2016) (PubMed).

Redmann, Benavides, Berryhill, Wani, Ouyang, Johnson, Ravi, Barnes, Darley-Usmar, Zhang: "Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons." in: Redox biology, Vol. 11, pp. 73-81, (2016) (PubMed).

Garofalo, Iovine, Kuryk, Capasso, Hirvinen, Vitale, Yliperttula, Bevilacqua, Cerullo: "Oncolytic Adenovirus Loaded with L-carnosine as Novel Strategy to Enhance the Antitumor Activity." in: Molecular cancer therapeutics, Vol. 15, Issue 4, pp. 651-60, (2016) (PubMed).

Morgan, Thorburn: "Measuring Autophagy in the Context of Cancer." in: Advances in experimental medicine and biology, Vol. 899, pp. 121-43, (2016) (PubMed).

Wilson, Nikolic, Kentish, Shalini, Hatzinikolas, Page, Dorstyn, Kumar: "Sex-specific alterations in glucose homeostasis and metabolic parameters during ageing of caspase-2-deficient mice." in: Cell death discovery, Vol. 2, pp. 16009, (2016) (PubMed).

Conlon, Thomas, Fedotova, Hernandez-Ono, Di Paolo, Chan, Ruggles, Gibeley, Liu, Ginsberg: "Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis." in: The Journal of clinical investigation, Vol. 126, Issue 10, pp. 3852-3867, (2016) (PubMed).

de Luxán-Delgado, Caballero, Potes, Rubio-González, Rodríguez, Gutiérrez-Rodríguez, Solano, Coto-Montes: "Melatonin administration decreases adipogenesis in the liver of ob/ob mice through autophagy modulation." in: Journal of pineal research, Vol. 56, Issue 2, pp. 126-33, (2015) (PubMed).

Niso-Santano, Malik, Pietrocola, Bravo-San Pedro, Mariño, Cianfanelli, Ben-Younès, Troncoso, Markaki, Sica, Izzo, Chaba, Bauvy, Dupont, Kepp, Rockenfeller, Wolinski, Madeo, Lavandero, Codogno, Harper et al.: "Unsaturated fatty acids induce non-canonical autophagy. ..." in: The EMBO journal, (2015) (PubMed).

Kucukgul, Ozler, Inci, Karakas, Irmak, Gozuacik, Taralp, Koc: "3D bioprinting of biomimetic aortic vascular constructs with self-supporting cells." in: Biotechnology and bioengineering, Vol. 112, Issue 4, pp. 811-21, (2015) (PubMed).

Li, Shi, He, Hu, Wang, Zhang, Chan, Chen: "Streptococcus pneumoniae induces autophagy through the inhibition of the PI3K-I/Akt/mTOR pathway and ROS hypergeneration in A549 cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122753, (2015) (PubMed).

Porta, Kwong, Trojanowski, Lee: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).

Yang, Peng, Ni, Li, Shi, Ding, Fan: "Basal Autophagy and Feedback Activation of Akt Are Associated with Resistance to Metformin-Induced Inhibition of Hepatic Tumor Cell Growth." in: PLoS ONE, Vol. 10, Issue 6, pp. e0130953, (2015) (PubMed).

Dou, Xu, Donahue, Shimi, Pan, Zhu, Ivanov, Capell, Drake, Shah, Catanzaro, Ricketts, Lamark, Adam, Marmorstein, Zong, Johansen, Goldman, Adams, Berger: "Autophagy mediates degradation of nuclear lamina." in: Nature, Vol. 527, Issue 7576, pp. 105-9, (2015) (PubMed).

Cinque, Forrester, Bartolomeo, Svelto, Venditti, Montefusco, Polishchuk, Nusco, Rossi, Medina, Polishchuk, De Matteis, Settembre: "FGF signalling regulates bone growth through autophagy." in: Nature, Vol. 528, Issue 7581, pp. 272-5, (2015) (PubMed).

Tung, Wang, Hsu, Hu, Her, Huang, Liao: "Presenilin-1 regulates the expression of p62 to govern p62-dependent tau degradation." in: Molecular neurobiology, Vol. 49, Issue 1, pp. 10-27, (2014) (PubMed).

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抗原

SQSTM1 (Sequestosome 1 (SQSTM1))

别名

SQSTM1

背景

Full Gene Name: sequestosome 1
Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B

基因ID

8878

途径

NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy