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EPM2A 抗体 (AA 101-199)

EPM2A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C6 unconjugated
产品编号 ABIN563505
发货至: 中国
  • 抗原 See all EPM2A 抗体
    EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))
    抗原表位
    • 10
    • 8
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-199
    适用
    • 43
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    宿主
    • 34
    • 8
    • 2
    小鼠
    克隆类型
    • 38
    • 6
    单克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    This EPM2A antibody is un-conjugated
    应用范围
    • 32
    • 25
    • 23
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Mouse monoclonal antibody raised against a partial recombinant EPM2A.
    序列
    GNGPHHDRCC TYNENNLVDG VYCLPIGHWI EATGHTNEMK HTTDFYFNIA GHQAMHYSRI LPNIWLGSCP RQVEHVTIKL KHELGITAVM NFQTEWDIV
    交叉反应
    人, 大鼠
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    EPM2A (NP_001018051, 101 a.a. ~ 199 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    6C6
    亚型
    IgG2a
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Irimia, Tagliabracci, Meyer, Segvich, DePaoli-Roach, Roach: "Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice." in: The Journal of biological chemistry, (2015) (PubMed).

    Zhu, Zhang, Kelly, Cheng: "The carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein-protein interactions." in: Bioscience reports, Vol. 34, Issue 4, (2014) (PubMed).

    Sherwood, Johnson, Delgado-Escueta, Gentry: "A bioassay for Lafora disease and laforin glucan phosphatase activity." in: Clinical biochemistry, Vol. 46, Issue 18, pp. 1869-76, (2013) (PubMed).

    DePaoli-Roach, Segvich, Meyer, Rahimi, Worby, Gentry, Roach: "Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity." in: Human molecular genetics, Vol. 21, Issue 7, pp. 1604-10, (2012) (PubMed).

    Tiberia, Turnbull, Wang, Ruggieri, Zhao, Pencea, Israelian, Wang, Ackerley, Wang, Liu, Minassian: "Increased laforin and laforin binding to glycogen underlie Lafora body formation in malin-deficient Lafora disease." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25650-9, (2012) (PubMed).

    Turnbull, Girard, Lohi, Chan, Wang, Tiberia, Omer, Ahmed, Bennett, Chakrabarty, Tyagi, Liu, Pencea, Zhao, Scherer, Ackerley, Minassian: "Early-onset Lafora body disease." in: Brain : a journal of neurology, Vol. 135, Issue Pt 9, pp. 2684-98, (2012) (PubMed).

    Turnbull, Wang, Girard, Ruggieri, Wang, Draginov, Kameka, Pencea, Zhao, Ackerley, Minassian: "Glycogen hyperphosphorylation underlies lafora body formation." in: Annals of neurology, Vol. 68, Issue 6, pp. 925-33, (2011) (PubMed).

    Tagliabracci, Turnbull, Wang, Girard, Zhao, Skurat, Delgado-Escueta, Minassian, Depaoli-Roach, Roach: "Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 49, pp. 19262-6, (2007) (PubMed).

  • 抗原
    EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))
    别名
    EPM2A (EPM2A 产品)
    别名
    TG-B antibody, Tg(TcraK,TcrbK)TG-BFlv antibody, EPM2 antibody, MELF antibody, laforin antibody, EPM2A, laforin glucan phosphatase antibody, epilepsy, progressive myoclonic epilepsy, type 2 gene alpha antibody, EPM2A antibody, Epm2a antibody
    背景
    Full Gene Name: epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
    Synonyms: EPM2,MELF
    基因ID
    7957
    NCBI登录号
    NM_001018041
    途径
    Cellular Glucan Metabolic Process
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