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MST1R 抗体 (Internal Region, pTyr1360)

MST1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5596950
发货至: 中国
  • 抗原 See all MST1R 抗体
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    抗原表位
    • 41
    • 21
    • 14
    • 12
    • 11
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region, pTyr1360
    适用
    • 98
    • 62
    • 41
    • 6
    • 2
    • 1
    • 1
    宿主
    • 109
    • 3
    • 2
    克隆类型
    • 103
    • 11
    多克隆
    标记
    • 38
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MST1R antibody is un-conjugated
    应用范围
    • 81
    • 35
    • 23
    • 21
    • 17
    • 15
    • 15
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    Cross-reactivity against RON from other species may occur but has not yet been tested.
    纯化方法
    Anti-RON pY1360 was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorptions against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for human RON protein phosphorylated at Y1360.
    免疫原

    Immunogen: Anti-RON pY1360 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide corresponding to residues surrounding Y1360 of human RON protein.

    Immunogen Type: Peptide

    亚型
    IgG
    Top Product
    Discover our top product MST1R Primary Antibody
  • 应用备注

    Application Note: Anti-RONpY1360 Antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a predominant band at ~ 152.3 kDa corresponding to full length protein by western blotting in the appropriate cell lysate or extract. This phospho-specific polyclonal antibody reacts with human RON pY1360 and shows minimal reactivity by ELISA against the non-phosphorylated form of the immunizing peptide.

    Western Blot Dilution: 1:500-1:2000

    ELISA Dilution: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.79 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    别名
    RON (MST1R 产品)
    别名
    CD136 antibody, CDw136 antibody, PTK8 antibody, RON antibody, Fv-2 antibody, Fv2 antibody, Ron antibody, STK antibody, Cdw136 antibody, Ptk8 antibody, Stk antibody, macrophage stimulating 1 receptor antibody, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antibody, MST1R antibody, Mst1r antibody
    背景

    Synonyms: Macrophage-stimulating protein receptor, p185-Ron, PTK8, RON, Protein-tyrosine kinase 8, c-met-related tyrosine kinase

    Background: RON pY1360 antibody detects phosphorylated RON. RON is a member of the protein kinase superfamily. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. RON is a heterodimer composed of an α chain and a β chain. The α chain is completely extracellular, whereas the β chain traverses the cell membrane and contains the intracellular tyrosine kinase and regulatory elements. Anti-RON Antibody is ideal for investigators involved in Cell Signaling, Cancer, Neuroscience and Signal Transduction research.

    Gene Name: MST1R

    基因ID
    4486
    UniProt
    Q04912
    途径
    RTK signaling
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