TLR6 抗体 (AA 280-512) (FITC)
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- 抗原 See all TLR6 抗体
- TLR6 (Toll-Like Receptor 6 (TLR6))
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抗原表位
- AA 280-512
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TLR6 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Recognizes human TLR6.
- 交叉反应
- 人
- 纯化方法
- Protein G purified.
- 免疫原
- Recombinant human TLR6 protein (aa 280-512).
- 克隆位点
- ABM1B50
- 亚型
- IgG1
- Top Product
- Discover our top product TLR6 Primary Antibody
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anti-Toll-Like Receptor 6 (TLR6) (AA 301-400) antibody
TLR6 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibodyTLR6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 393-423) antibodyTLR6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibodyTLR6 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 722-753) antibodyTLR6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 32-586) antibodyTLR6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 408-424) antibodyTLR6 适用: 人 FACS, IHC (p) 宿主: 小鼠 Monoclonal 86B1153-2 unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 608-796) antibodyTLR6 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (Center) antibodyTLR6 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 408-424) antibody (PE)TLR6 适用: 人 FACS 宿主: 小鼠 Monoclonal 86B1153-2 PE
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In 10 mM TRIS containing 150 mM NaCl and 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: +4°C
Stable for at least 6 months after receipt when stored at +4°C. - 有效期
- 6 months
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- 抗原
- TLR6 (Toll-Like Receptor 6 (TLR6))
- 别名
- TLR6 (TLR6 产品)
- 别名
- TLR1 antibody, TLR16 antibody, CD286 antibody, TLR-6 antibody, toll-like receptor 1 family member A antibody, toll like receptor 6 antibody, toll-like receptor 6 antibody, TLR1A antibody, TLR6 antibody, Tlr6 antibody
- 背景
- TLR6 (Toll-like Receptor 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 in complex with TLR2 specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides from Gram-positive bacteria and fungi. The activation cluster TLR2:TLR6:CD14:CD36 signals via MYD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. In complex with TLR2 recognizes MALP-2, STF, PSM and OspA-L, as well. In response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42, TLR6 forms a heterodimer with TLR4. This complex rapidly internalizes and triggers inflammatory responses through the NF-kappaB-dependent MYD88 signaling or via TICAM1 signaling pathways. The complex promotes sterile inflammation in monocytes/macrophages. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles)-induced inflammatory responses. Various polymorphism have been associated with inflammatory and tumor pathologies.
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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