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TLR9 抗体 (AA 100-290) (FITC)

TLR9 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal ABM1C51 FITC
产品编号 ABIN5564254
发货至: 中国
  • 抗原 See all TLR9 抗体
    TLR9 (Toll-Like Receptor 9 (TLR9))
    抗原表位
    • 18
    • 15
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-290
    适用
    • 90
    • 36
    • 12
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 62
    • 30
    • 7
    • 4
    • 1
    小鼠
    克隆类型
    • 71
    • 33
    单克隆
    标记
    • 58
    • 12
    • 12
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR9 antibody is conjugated to FITC
    应用范围
    • 73
    • 47
    • 43
    • 42
    • 22
    • 14
    • 11
    • 11
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    Recognizes human and mouse TLR9.
    交叉反应
    人, 小鼠
    纯化方法
    Protein G purified.
    免疫原
    Recombinant human TLR9 protein (aa 100-290).
    克隆位点
    ABM1C51
    亚型
    IgG1
    Top Product
    Discover our top product TLR9 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In 10 mM TRIS containing 150 mM NaCl and 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: +4°C
    Stable for at least 6 months after receipt when stored at +4°C.
    有效期
    6 months
  • 抗原
    TLR9 (Toll-Like Receptor 9 (TLR9))
    别名
    TLR9 (TLR9 产品)
    别名
    CD289 antibody, toll like receptor 9 antibody, toll-like receptor 9 antibody, TLR9 antibody, Tlr9 antibody
    背景
    TLR9 (Toll-like Receptor 9) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR9 is expressed by numerous cells of the immune system such as B lymphocytes, monocytes, natural killer (NK) cells and plasmacytoid dendritic cells. It is expressed intracellularly, within the endosomal compartments and functions to alert the immune system of viral and bacterial infections by binding to DNA rich in CpG motifs. This nucleotide-sensing TLR is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides (also called oligodinucleotides, ODNs), and consequently signals via MYD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response and eventually activation of a Th1-biased adaptive immune attack. Specific TLR9 agonists have been shown to have substantial antitumor activity, making the TLR9 signaling pathway an interesting target for therapeutic research.
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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