Retinoblastoma 1 抗体 (pSer807)
Quick Overview for Retinoblastoma 1 抗体 (pSer807) (ABIN5557520)
抗原
See all Retinoblastoma 1 (RB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pSer807
-
纯化方法
- Purified by Protein A.
-
免疫原
- Synthetic peptide derived from human Rb(S807), around 800-850aa (phospho S807).
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:1000-2000
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C
-
有效期
- 12 months
-
-
- Retinoblastoma 1 (RB1)
-
别名
- Rb
-
背景
-
Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Synonyms: RbSer780, OSRC, P105 RB, P105RB, PP105, PP110, pRb, RB 1, RB1, RB1 protein, Retinoblastoma 1 including osteosarcoma, Retinoblastoma 1, Retinoblastoma associated protein, Including osteosarcoma, Osteosarcoma, p105-Rb, Rb, RB_HUMAN, Retinoblastoma suspectibility protein, Retinoblastoma-associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene.
-
基因ID
- 5925
-
UniProt
- P06400
-
途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
抗原
-