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Retinoblastoma 1 抗体 (pSer807)

The 兔 单克隆 anti-Retinoblastoma 1 antibody (Clone 2D10) (ABIN5557520) specifically detects Retinoblastoma 1 in WB 和 IF (cc). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5557520
发货至: 中国
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Quick Overview for Retinoblastoma 1 抗体 (pSer807) (ABIN5557520)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

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  • 105
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  • 1
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人, 小鼠, 大鼠

宿主

  • 240
  • 29

克隆类型

  • 200
  • 69
单克隆

标记

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This Retinoblastoma 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

2D10
  • 抗原表位

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    • 1
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    pSer807

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide derived from human Rb(S807), around 800-850aa (phospho S807).

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存条件

    -20 °C

    储存方法

    Store at -20°C

    有效期

    12 months
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    Rb

    背景

    Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

    Synonyms: RbSer780, OSRC, P105 RB, P105RB, PP105, PP110, pRb, RB 1, RB1, RB1 protein, Retinoblastoma 1 including osteosarcoma, Retinoblastoma 1, Retinoblastoma associated protein, Including osteosarcoma, Osteosarcoma, p105-Rb, Rb, RB_HUMAN, Retinoblastoma suspectibility protein, Retinoblastoma-associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene.

    基因ID

    5925

    UniProt

    P06400

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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