ASAP3 抗体
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- 抗原 See all ASAP3 抗体
- ASAP3 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASAP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is directed against UPLC1/ASAP3 protein.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- Recombinant human UPLC1/ASAP3 protein
- 亚型
- IgG
- Top Product
- Discover our top product ASAP3 Primary Antibody
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anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 451-700) antibody
ASAP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) antibodyASAP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 26-54), (N-Term) antibodyASAP3 适用: 人, Hamster WB, IHC (p) 宿主: 兔 Polyclonal RB25488 unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 26-54), (N-Term) antibodyASAP3 适用: 人, Hamster WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 693-710) antibodyASAP3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 35-84) antibodyASAP3 适用: 人, 豚鼠, 马, 斑马鱼, Cow, 猴, Pig, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000 - 1/5,000. Western Blot: 1/1000 - 1/10,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.10 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
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- 抗原
- ASAP3 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))
- 别名
- DDEFL1 (ASAP3 产品)
- 别名
- DDEFL1 antibody, ddefl1 antibody, zgc:113885 antibody, ACAP4 antibody, CENTB6 antibody, UPLC1 antibody, 9430088F20Rik antibody, Ddefl1 antibody, Gm140 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 antibody, development and differentiation enhancing factor-like 1 antibody, ASAP3 antibody, asap3 antibody, DDEFL1 antibody, Asap3 antibody
- 背景
- UPLC1 (up-regulated in liver cancer 1), also named DDEFL1 (development and differentiation-enhancing factor-like 1) or ASAP3, is a member of the AZAP family of proteins. These proteins catalyze the hydrolysis of GTP bound to ADP-ribosylation factor (Arf) proteins, thereby causing Arf inactivation. For this reason, the ASAPs are generally called ArfGAPs. The activity of ArfGAPs is dependent on the presence of phosphoinositides and is implicated in cellular processes such as membrane trafficking and remodeling of the actin cytoskeleton. Both ASAP1 and ASAP3 have recently been implicated in the development of human cancers. Abnormal activity of ArfGAPs may lead to the alterations characteristic of malignant cells, such as the high rate of proliferation and invasion. More specifically, ASAP3 has been found to be up-regulated in 80 % of the hepatocellular carcinomas examined. Initial biochemical characterization reveals that ASAP3 shows class-specific GAP activity on Arf proteins, preferring Arf5 over Arf1 and Arf6.Synonyms: ACAP4, ANK repeat and PH domain-containing protein 3, ASAP3, Arf-GAP with SH3 domain, CENTB6, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1, UPLC1
- 基因ID
- 55616
- NCBI登录号
- NP_001137250
- UniProt
- Q8TDY4
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