(1 reference)-
- 抗原 See all ASAP3 抗体
- ASAP3 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASAP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 免疫原
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This antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant human UPLC1/ASAP3 protein.
Immunogentype:Recombinant - 亚型
- IgG
- Top Product
- Discover our top product ASAP3 Primary Antibody
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anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 451-700) antibody
ASAP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 26-54), (N-Term) antibodyASAP3 适用: 人, Hamster WB, IHC (p) 宿主: 兔 Polyclonal RB25488 unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 26-54), (N-Term) antibodyASAP3 适用: 人, Hamster WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 693-710) antibodyASAP3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) (AA 35-84) antibodyASAP3 适用: 人, Cow, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This protein A purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 100 kDa in size corresponding to UPLC1/ASAP3 protein by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "Loss of ASAP3 destabilizes cytoskeletal protein ACTG1 to suppress cancer cell migration." in: Molecular medicine reports, Vol. 9, Issue 2, pp. 387-94, (2014) (PubMed).
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: "Loss of ASAP3 destabilizes cytoskeletal protein ACTG1 to suppress cancer cell migration." in: Molecular medicine reports, Vol. 9, Issue 2, pp. 387-94, (2014) (PubMed).
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- 抗原
- ASAP3 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))
- 别名
- Uplc1/Asap3 (ASAP3 产品)
- 别名
- DDEFL1 antibody, ddefl1 antibody, zgc:113885 antibody, ACAP4 antibody, CENTB6 antibody, UPLC1 antibody, 9430088F20Rik antibody, Ddefl1 antibody, Gm140 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 antibody, development and differentiation enhancing factor-like 1 antibody, ASAP3 antibody, asap3 antibody, DDEFL1 antibody, Asap3 antibody
- 背景
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This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Anti-UPLC1 (up-regulated in liver cancer 1) / ASAP3 Antibody, also named DDEFL1 (development and differentiation-enhancing factor-like 1) or ASAP3, is a member of the AZAP family of proteins. These proteins catalyze the hydrolysis of GTP bound to ADP-ribosylation factor (Arf) proteins, thereby causing Arf inactivation. For this reason, the ASAPs are generally called ArfGAPs. The activity of ArfGAPs is dependent on the presence of phosphoinositides and is implicated in cellular processes such as membrane trafficking and remodeling of the actin cytoskeleton. ASAP3 has been found to be up-regulated in 80% of the hepatocellular carcinomas examined. Initial biochemical characterization reveals that ASAP3 shows class-specific GAP activity on Arf proteins, preferring Arf5 over Arf1 and Arf6. ASAP3 antibody has beed developed through the NCI antibody collaboration program and is ideal for Cancer and Signal Transduction research.
Synonyms: ASAP3 Antibody, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, FLJ20199 antibody, Gm140 antibody - 基因ID
- 55616, 19071867
- UniProt
- Q8TDY4
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