BCL2L1 抗体 (pThr115)
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北京 101111
Quick Overview for BCL2L1 抗体 (pThr115) (ABIN5541071)
抗原
See all BCL2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr115
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序列
- TSQLHITpPG TAY
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特异性
- This antibody detects Human and other species with consensus Bcl-xL peptide (TSQLHITpPGTAY).
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纯化方法
- Protein G affinity
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免疫原
- A synthetic peptide derived from Threonine 115 phosphorylated Bcl-xL, conjugated with KLH
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应用备注
- ELISA: The antibody, when 1:10,000 1:100,000 diluted, can detect the Threonine 115 phosphorylated Bcl-xL coated on ELISA plate.
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限制
- 仅限研究用
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缓冲液
- 0.01M PBS, pH 7.4
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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别名
- bcl-2-like 1
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背景
- Bcl-xL is a prosurvival factor in the Bcl-2 family. It is a mitochondrial outer membrane protein that regulates the voltage-dependent anion channels (VDAC), and controls the production of reactive oxygen species and the release of cytochrome C. Bcl-xL gene knock-out resulted in embryonic lethality in animal model due to neuronal apoptosis and erythroid apoptosis. Bcl-xL is believed to be involved with the survival and differentiation of erythroid cells, iron metabolism and hemoglobin synthesis.
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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