BCL2L1 抗体 (AA 1-219)
(4 references)-
- 抗原 See all BCL2L1 抗体
- BCL2L1 (BCL2-Like 1 (BCL2L1))
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抗原表位
- AA 1-219
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCL2L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Bcl-2-like protein 1(BCL2L1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Bcl-2-like protein 1(BCL2L1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: BCL2-like 1
Protein Name: Bcl-2-like protein 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Bcl-XL recombinant protein (Position: M1-T219). Human Bcl-XL shares 97.9% amino acid (aa) sequence identity with both mouse and rat Bcl-XL.
- 亚型
- IgG
- Top Product
- Discover our top product BCL2L1 Primary Antibody
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anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2-2A5 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-120) antibodyBCL2L1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) antibodyBCL2L1 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibodyBCL2L1 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 81-200) antibodyBCL2L1 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) antibodyBCL2L1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-209) antibodyBCL2L1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Active targeting co-delivery system based on hollow mesoporous silica nanoparticles for antitumor therapy in ovarian cancer stem-like cells." in: Oncology reports, Vol. 38, Issue 3, pp. 1442-1450, (2018) (PubMed).
: "Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 5121-5128, (2018) (PubMed).
: "Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 9390810, (2018) (PubMed).
: "Azithromycin synergistically enhances anti-proliferative activity of vincristine in cervical and gastric cancer cells." in: Cancers, Vol. 4, Issue 4, pp. 1318-32, (2013) (PubMed).
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: "Active targeting co-delivery system based on hollow mesoporous silica nanoparticles for antitumor therapy in ovarian cancer stem-like cells." in: Oncology reports, Vol. 38, Issue 3, pp. 1442-1450, (2018) (PubMed).
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- 抗原
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- 别名
- BCL2L1 (BCL2L1 产品)
- 别名
- BCL-XL/S antibody, BCL2L antibody, BCLX antibody, BCLXL antibody, BCLXS antibody, Bcl-X antibody, PPP1R52 antibody, bcl-xL antibody, bcl-xS antibody, Bcl(X)L antibody, Bcl-XL antibody, Bcl-Xs antibody, Bcl2l antibody, BclX antibody, bcl-x antibody, Bcl-xl antibody, Bclx antibody, bcl-X antibody, Bcl-xL antibody, BCL-XL antibody, BCL2L1 antibody, bcl-XL antibody, bcl-x(l) antibody, bcl-xl/s antibody, bcl-xs antibody, bcl2l antibody, bclx antibody, bclxl antibody, xR11 antibody, bcl-xl antibody, blp1 antibody, cb1021 antibody, zfBLP1 antibody, BCL2 like 1 antibody, BCL2-like 1 antibody, Bcl2-like 1 antibody, BCL2-like 1 L homeolog antibody, bcl2-like 1 antibody, BCL2L1 antibody, Bcl2l1 antibody, bcl2l1 antibody, bcl2l1.L antibody
- 背景
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Bcl-2-like protein 1, also known as Bcl-XL, is a protein that in humans is encoded by the BCL2L1 gene. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator.
Synonyms: Bcl X | Bcl xL | BCL XL/S | Bcl xS | Bcl2-L-1 | BCL2L | Bcl2l1 | BCLX | BclXL | BclXs | PPP1R52 | Q07817 - 基因ID
- 598
- UniProt
- Q07817
- 途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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