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BCL2L1 抗体 (AA 1-219)

Name: BCL2L1 抗体 (AA 1-219)
SKU: ABIN5518741
Availability: OutOfStock

There are 4+ publications for this product available. The 兔多克隆 anti-BCL2L1 antibody is suitable to detect BCL2L1 in samples from 人, 大鼠和小鼠. It has been validated for WB, IHC, IF, FACS, IP 和 ICC.

Western blot analysis of Bcl-XL using anti-Bcl-XL antibody . (BCL2L1 抗体 (AA 1-219))

IHC analysis of Bcl-XL using anti-Bcl-XL antibody (ABIN5518741). (BCL2L1 抗体 (AA 1-219))

IHC

IHC analysis of Bcl-XL using anti-Bcl-XL antibody . (BCL2L1 抗体 (AA 1-219))

IHC

Western blot analysis of Bcl-XL using anti-Bcl-XL antibody (ABIN5518741). (BCL2L1 抗体 (AA 1-219))

Flow Cytometry analysis of Jurkat cells using anti-Bcl-XL antibody (ABIN5518741). (BCL2L1 抗体 (AA 1-219))

FACS

IF analysis of Bcl-XL using anti-Bcl-XL antibody (ABIN5518741). (BCL2L1 抗体 (AA 1-219))

IHC

Immunoprecipitating (IP) Bcl-XL in A549 whole cell lysate. (BCL2L1 抗体 (AA 1-219))

9 images

(4 references)

产品编号 ABIN5518741

发货至: 中国

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Quick Overview for BCL2L1 抗体 (AA 1-219) (ABIN5518741)

抗原

See all BCL2L1 抗体

BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This BCL2L1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Discover our top product BCL2L1 Primary Antibody

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AA 1-219

原理

Anti-Bcl-XL/BCL2L1 Antibody

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

Human Bcl-XL shares 97.9% amino acid (aa) sequence identity with both mouse,rat Bcl-XL.

产品特性

Anti-Bcl-XL/BCL2L1 Antibody. Tested in Flow Cytometry, IP, ICC/IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Bcl-XL recombinant protein (Position: M1-T219). Human Bcl-XL shares 97.9% amino acid (aa) sequence identity with both mouse and rat Bcl-XL.

亚型

IgG
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 适用: 人 WB, IF, ELISA, PLA 宿主: 小鼠 Monoclonal 3E2-2A5 unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 1-120) antibody
BCL2L1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) antibody
BCL2L1 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibody
BCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibody
BCL2L1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibody
BCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 81-200) antibody
BCL2L1 适用: 人, 大鼠, 小鼠, Pig, 绵羊 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (pSer62) antibody
BCL2L1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (N-Term) antibody
BCL2L1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Guo, Guo, Zhao, Cai: "Active targeting co-delivery system based on hollow mesoporous silica nanoparticles for antitumor therapy in ovarian cancer stem-like cells." in: Oncology reports, Vol. 38, Issue 3, pp. 1442-1450, (2018) (PubMed).

Cui, Li, Xu, Zhang, Sun, Chen: "Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 5121-5128, (2018) (PubMed).

Liu, Lin, Mi, Li, Zhang: "Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 9390810, (2018) (PubMed).

Zhou, Zhang, Li, Hao, Liu, Wang: "Azithromycin synergistically enhances anti-proliferative activity of vincristine in cervical and gastric cancer cells." in: Cancers, Vol. 4, Issue 4, pp. 1318-32, (2013) (PubMed).
抗原

BCL2L1 (BCL2-Like 1 (BCL2L1))

别名

BCL2L1

背景

Background: Bcl-2-like protein 1, also known as Bcl-XL, is a protein that in humans is encoded by the BCL2L1 gene. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator.
Gene Full Name: BCL2 like 1

分子量

30 kDa

基因ID

598

UniProt

Q07817

途径

Apoptosis, Negative Regulation of intrinsic apoptotic Signaling