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ULBP2 抗体 (AA 88-116)

ULBP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5537948
发货至: 中国
  • 抗原 See all ULBP2 抗体
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 88-116
    适用
    • 23
    • 1
    • 1
    宿主
    • 18
    • 5
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This ULBP2 antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This ULBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human ULBP2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ULBP2 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    别名
    ULBP2 (ULBP2 产品)
    别名
    N2DL2 antibody, RAET1H antibody, UL16 binding protein 2 antibody, NKG2D ligand 2-like antibody, ULBP2 antibody, LOC100355436 antibody
    背景
    Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
    分子量
    27 kDa
    基因ID
    80328
    UniProt
    Q9BZM5
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