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SH2D1A 抗体 (C-Term)

SH2D1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5537526
发货至: 中国
  • 抗原 See all SH2D1A 抗体
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    抗原表位
    • 14
    • 9
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 85-114, C-Term
    适用
    • 51
    • 19
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 47
    • 3
    • 1
    • 1
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH2D1A antibody is un-conjugated
    应用范围
    • 47
    • 20
    • 13
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SH2D1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the C-terminal region of human SH2D1A.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SH2D1A Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    别名
    SH2D1A (SH2D1A 产品)
    别名
    DSHP antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, XLP antibody, XLPD antibody, RGD1562408 antibody, Gm686 antibody, SH2D1A antibody, SH2 domain containing 1A antibody, SH2D1A antibody, Sh2d1a antibody
    背景
    This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    14 kDa
    基因ID
    4068
    UniProt
    O60880
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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