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- 抗原 See all NR4A2 抗体
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
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抗原表位
- AA 13-42, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR4A2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- 免疫原
- This NURR1 (NR4A2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human NURR1 (NR4A2).
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NR4A2 Primary Antibody
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anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 71-170) antibody
NR4A2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A6 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 164-197) antibodyNR4A2 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52431 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibodyNR4A2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔, Pig, Bat, 小鸡, Hamster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42), (N-Term) antibodyNR4A2 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7385 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-335) antibodyNR4A2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) antibodyNR4A2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-598) antibodyNR4A2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IF starting dilution is: 1:10~50 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
- 别名
- NURR1 (NR4A2 产品)
- 别名
- nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody
- 背景
- Parkinson's disease (PD) is a multifactorial disease that appears to arise from the effects of both genetic and environmental influences. The known genetic factors include multiple genes that have been identified in related parkinsonian syndromes, as well as alpha-synuclein. Genes associated with either PD or Parkinson-related disorders include parkin, DJ-1, ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1), nuclear receptor-related factor 1 (NURR1), and alpha-synuclein. Nurr1 is a transcription factor that is expressed in the embryonic ventral midbrain and is critical for the development of dopamine (DA) neurons. It belongs to the conserved family of nuclear receptors but lacks an identified ligand and is therefore referred to as an orphan receptor. RXR ligands can promote the survival of DA neurons via a process that depends on Nurr1-RXR heterodimers. In developing DA cells, Nurr1 is required for the expression of several genes important for DA synthesis and function. Nurr1 is also important for the maintenance of adult DA neurons.
- 分子量
- 67 kDa
- 基因ID
- 4929
- UniProt
- P43354
- 途径
- Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
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