NR4A2 抗体 (AA 13-42)
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- 抗原 See all NR4A2 抗体
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
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抗原表位
- AA 13-42
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR4A2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应 （详细）
- Expected species reactivity: Rat, Bovine
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 13-42 from the human protein was used as the immunogen for this NURR1 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NR4A2 Primary Antibody
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anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 71-170) antibody
NR4A2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A6 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 164-197) antibodyNR4A2 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52431 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔, Pig, Bat, 小鸡, Hamster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42), (N-Term) antibodyNR4A2 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7385 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-335) antibodyNR4A2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) antibodyNR4A2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-598) antibodyNR4A2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) antibodyMicroarray verified NR4A2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB773479 unconjugated
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- 应用备注
- Titration of the NURR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the NURR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
- 别名
- NURR1 (NR4A2 产品)
- 别名
- nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody
- 背景
- Parkinson's disease (PD) is a multifactorial disease that appears to arise from the effects of both genetic and environmental influences. The known genetic factors include multiple genes that have been identified in related parkinsonian syndromes, as well as alpha-synuclein. Genes associated with either PD or Parkinson-related disorders include parkin, DJ-1, ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1), nuclear receptor-related factor 1 (NURR1), and alpha-synuclein. Nurr1 is a transcription factor that is expressed in the embryonic ventral midbrain and is critical for the development of dopamine (DA) neurons. It belongs to the conserved family of nuclear receptors but lacks an identified ligand and is therefore referred to as an orphan receptor. RXR ligands can promote the survival of DA neurons via a process that depends on Nurr1-RXR heterodimers. In developing DA cells, Nurr1 is required for the expression of several genes important for DA synthesis and function. Nurr1 is also important for the maintenance of adult DA neurons.
- UniProt
- P43354
- 途径
- Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
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