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- 抗原 See all STK3 抗体
- STK3 (serine/threonine Kinase 3 (STK3))
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抗原表位
- AA 387-415, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse Stk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of mouse Stk3.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product STK3 Primary Antibody
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anti-serine/threonine Kinase 3 (STK3) (AA 323-450) antibody
STK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) antibodySTK3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 1-491) antibodySTK3 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 311-431) antibodySTK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-serine/threonine Kinase 3 (STK3) (C-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) antibodySTK3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (N-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 兔, 马, Pig, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 396-425), (C-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal RB1196 unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 1-491) antibodySTK3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 253-350) antibodySTK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
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- 应用备注
- For WB starting dilution is: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- STK3 (serine/threonine Kinase 3 (STK3))
- 别名
- Stk3 (STK3 产品)
- 别名
- KRS1 antibody, MST2 antibody, 0610042I06Rik antibody, MST antibody, Mst2 antibody, Mst3 antibody, Ste20 antibody, mess1 antibody, mst2 antibody, xstk3 antibody, wu:fc19e11 antibody, zgc:55383 antibody, serine/threonine kinase 3 antibody, serine/threonine kinase 3 S homeolog antibody, serine/threonine kinase 3 (STE20 homolog, yeast) antibody, STK3 antibody, Stk3 antibody, stk3.S antibody, stk3 antibody
- 背景
- Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. MST1/MST2 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation. Phosphorylates NKX2-1.
- 分子量
- 57 kDa
- 基因ID
- 56274
- UniProt
- Q9JI10
- 途径
- Tube Formation
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