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NOTCH3 抗体 (C-Term)

NOTCH3 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5534576
发货至: 中国
  • 抗原 See all NOTCH3 抗体
    NOTCH3 (Notch 3 (NOTCH3))
    抗原表位
    • 14
    • 11
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 2291-2321, C-Term
    适用
    • 50
    • 16
    • 11
    • 1
    小鼠
    宿主
    • 34
    • 16
    • 2
    • 1
    • 1
    克隆类型
    • 38
    • 17
    多克隆
    标记
    • 30
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH3 antibody is un-conjugated
    应用范围
    • 27
    • 25
    • 22
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This NOTCH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3.
    亚型
    Ig Fraction
    Top Product
    Discover our top product NOTCH3 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IF starting dilution is: 1:10~50

    For IHC-P starting dilution is: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    NOTCH3 (Notch 3 (NOTCH3))
    别名
    NOTCH3 (NOTCH3 产品)
    别名
    CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
    背景
    NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
    分子量
    244 kDa
    基因ID
    4854
    UniProt
    Q9UM47
    途径
    Notch Signaling
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