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- 抗原 See all STUB1 抗体
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
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抗原表位
- AA 203-231, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STUB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- 免疫原
- This STUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human STUB1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product STUB1 Primary Antibody
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anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibodySTUB1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, Pig, 马, 猴, 小鸡, Hamster, Avian, Cat, 驴, 山羊, 兔, 绵羊 WB 宿主: 山羊 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibodyVerified STUB1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231) antibodySTUB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibodySTUB1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibodySTUB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-48) antibodySTUB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 160-190) antibodySTUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibodySTUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231), (C-Term) antibodySTUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7393 unconjugated
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- 应用备注
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
- 别名
- STUB1 (STUB1 产品)
- 别名
- CHIP antibody, HSPABP2 antibody, NY-CO-7 antibody, SDCCAG7 antibody, UBOX1 antibody, 0610033N24Rik antibody, 2210017D18Rik antibody, 2310040B03Rik antibody, AW046544 antibody, Chip antibody, wu:fc22f04 antibody, zgc:56076 antibody, STUB1 antibody, chip antibody, ATCHIP antibody, CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN antibody, carboxyl terminus of HSC70-interacting protein antibody, STIP1 homology and U-box containing protein 1 antibody, STIP1 homology and U-Box containing protein 1 antibody, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase L homeolog antibody, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase antibody, STIP1 homology and U box-containing protein 1 antibody, carboxyl terminus of HSC70-interacting protein antibody, STUB1 antibody, Stub1 antibody, stub1 antibody, stub1.L antibody, LOC100282870 antibody, CHIP antibody
- 背景
- CHIP is an E3 ligase for nNOS whose action is facilitated by (and possibly requires) its interaction with nNOS-bound hsp70. Co-chaperone CHIP, possibly with another E3 ligase(s), modulates the ubiquitylation of mutant Cu/Zn-superoxide dismutase and renders them more susceptible for proteasomal degradation. CHIP functions as a negative regulator of AR transcriptional activity by promoting AR degradation. CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. CHIP can interact with the Smad1/Smad4 proteins and block BMP signal transduction through the ubiquitin-mediated degradation of Smad proteins. CHIP E3 controls both the association of Hsp70/Hsp90 chaperones with ErbB2 and the down-regulation of ErbB2 induced by inhibitors of Hsp90. CHIP is associated with Parkin and enhances its ubiquitin ligase activity related to Parkinson's disease.
- 分子量
- 35 kDa
- 基因ID
- 10273
- UniProt
- Q9UNE7
- 途径
- Regulation of Hormone Metabolic Process, Response to Water Deprivation
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