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STUB1 抗体 (C-Term)

Name: STUB1 抗体 (C-Term)
SKU: ABIN390386
Availability: OutOfStock

STUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7393 unconjugated

CHIP Antibody (C-term) (ABIN390386 and ABIN2837936) western blot analysis in 293 cell line and human placenta lysates (35 μg/lane). (STUB1 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (STUB1 抗体 (C-Term))

IHC (p)

Anti-CHIP C-term at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. (STUB1 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CHIP (STUB1) antibody (C-term) (ABIN390386 and ABIN2837936) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (STUB1 抗体 (C-Term))

IHC (p)

4 images

产品编号 ABIN390386

发货至: 中国

Datasheet as PDF

抗原 See all STUB1 抗体

STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
抗原表位
15

10

8

6

5

3

2

2

2

2

1

1

1

1

1

1
AA 203-231, C-Term
适用
67

37

33

6

6

4

4

3

3

3

2

2

2

1

1

1

1

1

1

1
人
宿主
60

5

2
兔
Compatible Secondaries
克隆类型
55

12
多克隆
标记
33

5

5

3

2

2

2

2

2

2

2

2

1

1

1

1

1
This STUB1 antibody is un-conjugated
应用范围
54

26

14

13

13

12

11

8

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

C, M

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This STUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human STUB1.

克隆位点

RB7393

亚型

Ig Fraction

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anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibody
STUB1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, Pig, 马, 小鸡, 猴, Hamster, Avian, Cat, 驴, 山羊, 兔, 绵羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibody
Verified STUB1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231) antibody
STUB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibody
STUB1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-48) antibody
STUB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 160-190) antibody
STUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibody
STUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (N-Term) antibody
STUB1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

别名

CHIP (STUB1) (STUB1 产品)

别名

CHIP antibody, HSPABP2 antibody, NY-CO-7 antibody, SDCCAG7 antibody, UBOX1 antibody, 0610033N24Rik antibody, 2210017D18Rik antibody, 2310040B03Rik antibody, AW046544 antibody, Chip antibody, wu:fc22f04 antibody, zgc:56076 antibody, STUB1 antibody, chip antibody, ATCHIP antibody, CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN antibody, carboxyl terminus of HSC70-interacting protein antibody, STIP1 homology and U-box containing protein 1 antibody, STIP1 homology and U-Box containing protein 1 antibody, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase L homeolog antibody, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase antibody, STIP1 homology and U box-containing protein 1 antibody, carboxyl terminus of HSC70-interacting protein antibody, STUB1 antibody, Stub1 antibody, stub1 antibody, stub1.L antibody, LOC100282870 antibody, CHIP antibody

背景

CHIP is an E3 ligase for nNOS whose action is facilitated by (and possibly requires) its interaction with nNOS-bound hsp70. Co-chaperone CHIP, possibly with another E3 ligase(s), modulates the ubiquitylation of mutant Cu/Zn-superoxide dismutase and renders them more susceptible for proteasomal degradation. CHIP functions as a negative regulator of AR transcriptional activity by promoting AR degradation. CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. CHIP can interact with the Smad1/Smad4 proteins and block BMP signal transduction through the ubiquitin-mediated degradation of Smad proteins. CHIP E3 controls both the association of Hsp70/Hsp90 chaperones with ErbB2 and the down-regulation of ErbB2 induced by inhibitors of Hsp90. CHIP is associated with Parkin and enhances its ubiquitin ligase activity related to Parkinson's disease.

分子量

34856

基因ID

10273

NCBI登录号

NP_005852

UniProt

Q9UNE7

途径

Regulation of Hormone Metabolic Process, Response to Water Deprivation