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HYOU1 抗体 (AA 274-303)

HYOU1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532765
发货至: 中国
  • 抗原 See all HYOU1 抗体
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    抗原表位
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 274-303
    适用
    • 64
    • 27
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 21
    克隆类型
    • 39
    • 27
    多克隆
    标记
    • 27
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HYOU1 antibody is un-conjugated
    应用范围
    • 56
    • 18
    • 15
    • 14
    • 14
    • 13
    • 13
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This HYOU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the Central region of human HYOU1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product HYOU1 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For IF starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    别名
    HYOU1 (HYOU1 产品)
    别名
    GRP-170 antibody, Grp170 antibody, HSP12A antibody, ORP-150 antibody, ORP150 antibody, AI415631 antibody, CBP-140 antibody, Cab140 antibody, Orp150 antibody, id:ibd5056 antibody, wu:fd14c05 antibody, zgc:56019 antibody, HYOU1 antibody, orp150 antibody, GRP170 antibody, hypoxia up-regulated 1 antibody, hypoxia up-regulated protein 1 antibody, hypoxia up-regulated 1 S homeolog antibody, HYOU1 antibody, Hyou1 antibody, hyou1 antibody, LOC100380749 antibody, hyou1.S antibody
    背景
    HYOU1 belongs to the heat shock protein 70 family. The protein is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal.
    分子量
    111 kDa
    基因ID
    10525
    UniProt
    Q9Y4L1
    途径
    ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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