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- 抗原 See all SYVN1 抗体
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
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抗原表位
- AA 586-617, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SYVN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- 免疫原
- This SYVN1 (HRD1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-617 amino acids from the C-terminal region of human SYVN1 (HRD1).
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SYVN1 Primary Antibody
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anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 586-617), (C-Term) antibody
SYVN1 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB4822 unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 586-617) antibodySYVN1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodyVerified SYVN1 适用: 人, 大鼠 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 531-617) antibodySYVN1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodySYVN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 338-487) antibodySYVN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodySYVN1 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, Bat, 猴, 斑马鱼, Hamster, 非洲爪蟾 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 1-617) antibodySYVN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 238-318) antibodySYVN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 501-550) antibodySYVN1 适用: 人, 小鼠, 大鼠, 马, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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For WB starting dilution is: 1:2000
For IF starting dilution is: 1:200
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
- 别名
- SYVN1 (SYVN1 产品)
- 别名
- DER3 antibody, HRD1 antibody, hrd1 antibody, 1200010C09Rik antibody, AW211966 antibody, C85322 antibody, D530017H19Rik antibody, Hrd1 antibody, RGD1310488 antibody, syvn1 antibody, syvn1-a antibody, syvn1-b antibody, wu:fk91f10 antibody, zgc:55735 antibody, zgc:77108 antibody, synoviolin 1 antibody, synovial apoptosis inhibitor 1, synoviolin antibody, synoviolin 1 S homeolog antibody, SYVN1 antibody, syvn1 antibody, Syvn1 antibody, syvn1.S antibody
- 背景
- HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.
- 分子量
- 68 kDa
- 基因ID
- 84447
- UniProt
- Q86TM6
- 途径
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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