This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This DMRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the C-terminal region of human DMRT1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
DMRT1
(Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
DMT1 antibody, DMRT1 antibody, zgc:136676 antibody, dmrt1 antibody, dmrt1-alpha antibody, dmt1 antibody, dmrt1-beta antibody, xdmrt1 antibody, doublesex and mab-3 related transcription factor 1 antibody, doublesex and mab-3 related transcription factor 1 L homeolog antibody, doublesex and mab-3 related transcription factor 1 S homeolog antibody, DMRT1 antibody, Dmrt1 antibody, dmrt1 antibody, dmrt1.L antibody, dmrt1.S antibody
背景
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.