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DMRT1 抗体 (AA 195-363)

DMRT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7150637
发货至: 中国
  • 抗原 See all DMRT1 抗体
    DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
    抗原表位
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    AA 195-363
    适用
    • 35
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 28
    • 8
    克隆类型
    • 30
    • 6
    多克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    This DMRT1 antibody is un-conjugated
    应用范围
    • 32
    • 17
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
    别名
    DMRT1 (DMRT1 产品)
    别名
    DMT1 antibody, DMRT1 antibody, zgc:136676 antibody, dmrt1 antibody, dmrt1-alpha antibody, dmt1 antibody, dmrt1-beta antibody, xdmrt1 antibody, doublesex and mab-3 related transcription factor 1 antibody, doublesex and mab-3 related transcription factor 1 L homeolog antibody, doublesex and mab-3 related transcription factor 1 S homeolog antibody, DMRT1 antibody, Dmrt1 antibody, dmrt1 antibody, dmrt1.L antibody, dmrt1.S antibody
    背景

    Background: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).

    Aliases: CT154 antibody, DM domain expressed in testis 1 antibody, DM domain expressed in testis protein 1 antibody, DM domain gene expressed in testis antibody, DMRT 1 antibody, dmrt1 antibody, DMRT1_HUMAN antibody, DMT 1 antibody, DMT1 antibody, Doublesex and mab 3 related transcription factor 1 antibody, Doublesex- and mab-3-related transcription factor 1 antibody

    UniProt
    Q9Y5R6
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