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STAT1 抗体 (AA 2-230)

Name: STAT1 抗体 (AA 2-230)
SKU: ABIN5518871
Availability: OutOfStock

STAT1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot analysis of STAT1 using anti-STAT1 antibody . (STAT1 抗体 (AA 2-230))

IHC analysis of STAT1 using anti- STAT1 antibody . (STAT1 抗体 (AA 2-230))

IHC

2 images

(2 references)

产品编号 ABIN5518871

发货至: 中国

Datasheet as PDF

抗原 See all STAT1 抗体

STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
抗原表位
45

30

16

15

13

7

6

5

5

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2-230
适用
171

99

71

18

18

16

15

13

11

7

6

5

4

4

2

1

1
人, 小鼠, 大鼠
宿主
172

17

2
兔
Compatible Secondaries
克隆类型
162

29
多克隆
标记
106

11

9

8

6

5

5

5

5

5

4

3

3

3

3

3

3

2

2
This STAT1 antibody is un-conjugated
应用范围
132

64

50

43

36

26

26

20

19

7

6

4

3

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Signal transducer and activator of transcription 1-alpha/beta(STAT1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Signal transducer and activator of transcription 1-alpha/beta(STAT1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: signal transducer and activator of transcription 1, 91 kDa
Protein Name: Signal transducer and activator of transcription 1-alpha/beta

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human STAT1 recombinant protein (Position: S2-A230). Human STAT1 shares 91.2% amino acid (aa) sequence identity with mouse STAT1.

亚型

IgG

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anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 343-602) antibody
STAT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibody
STAT1 适用: 人, 犬, 猴 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 4H9 unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 717-745), (C-Term) antibody
STAT1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB41406 unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibody
STAT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 650-750) antibody
STAT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 513-712) antibody
STAT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibody
STAT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) antibody
STAT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Gong, Cao, Jiang, Zhou, Liu: "Hepatitis C virus non-structural 5A abrogates signal transducer and activator of transcription-1 nuclear translocation induced by IFN-alpha through dephosphorylation." in: World journal of gastroenterology, Vol. 13, Issue 30, pp. 4080-4, (2007) (PubMed).
抗原

STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

别名

STAT1 (STAT1 产品)

别名

CANDF7 antibody, ISGF-3 antibody, STAT91 antibody, 2010005J02Rik antibody, AA408197 antibody, XStat1 antibody, STAT4 antibody, DD6G4-4 antibody, STAT antibody, STAT1 antibody, dZ182H3.3 antibody, si:by134g18.2 antibody, si:by51f19.1 antibody, si:dz182h3.3 antibody, si:dz199m19.1 antibody, si:dz73o4.2 antibody, stat1 antibody, signal transducer and activator of transcription 1 antibody, signal transducer and activator of transcription 1 L homeolog antibody, signal transducer and activator of transcription 1, 91kDa antibody, signal transducer and activator of transcription 4 antibody, signal transducer and activator of transcription 1a antibody, STAT1 antibody, Stat1 antibody, stat1.L antibody, stat4 antibody, stat1a antibody

背景

Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Synonyms: Signal transducer and activator of transcription 1-alpha/beta | Transcription factor ISGF-3 components p91/p84 | STAT1 | STAT 1 | P42224

基因ID

6772

UniProt

P42224

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events