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Superoxide dismutase copper chaperone 抗体 (C-Term)

CCS 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518744
发货至: 中国
  • 抗原 See all Superoxide dismutase copper chaperone (CCS) 抗体
    Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))
    抗原表位
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    AA 174-209, C-Term
    适用
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    人, 小鼠, 大鼠
    宿主
    • 54
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    克隆类型
    • 56
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    多克隆
    标记
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    This Superoxide dismutase copper chaperone antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Copper chaperone for superoxide dismutase(CCS) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    DADGRAIFRM EDEQLKVWDV IGRSLIIDEG EDDLGR
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Copper chaperone for superoxide dismutase(CCS) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: copper chaperone for superoxide dismutase
    Protein Name: Copper chaperone for superoxide dismutase
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human CCS (174-209aa DADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGR), different from the related mouse sequence by six amino acids, and from the related rat sequence by seven amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CCS Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))
    别名
    CCS (CCS 产品)
    别名
    ccs antibody, MGC82563 antibody, CCS antibody, DDBDRAFT_0189222 antibody, DDBDRAFT_0238038 antibody, DDB_0189222 antibody, DDB_0238038 antibody, ATCCS antibody, COPPER/ZINC SUPEROXIDE DISMUTASE COPPER CHAPERONE antibody, F5O11.26 antibody, F5O11_26 antibody, copper chaperone for SOD1 antibody, Ccsd antibody, copper chaperone for superoxide dismutase L homeolog antibody, copper chaperone for superoxide dismutase antibody, copper chaperone for SOD1 antibody, ccs.L antibody, ccs antibody, CCS antibody, LOC552629 antibody, Ccs antibody
    背景
    Copper chaperone for superoxide dismutase is a metalloprotein that is responsible for the delivery of Cu to superoxide dismutase (SOD1). In humans the protein is encoded by the CCS gene. And this gene is mapped to chromosome 11q13 by fluorescence in situ hybridization. The CCS protein is present in mammals and most eukaryotes including yeast. The structure of CCS is composed of three distinct domains that are necessary for its function. Although CCS is important for many organisms, there are CCS independent pathways for SOD1, and many species lack CCS all together, such as C. elegans.

    Synonyms: CCS | SOD 4 | SOD4 | O14618
    基因ID
    9973
    UniProt
    O14618
    途径
    Transition Metal Ion Homeostasis
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