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AGT 抗体 (AA 25-115)

AGT 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518727
发货至: 中国
  • 抗原 See all AGT 抗体
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    抗原表位
    • 16
    • 15
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    • 8
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    • 5
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    • 2
    • 1
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    AA 25-115
    适用
    • 116
    • 51
    • 49
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    小鼠
    宿主
    • 102
    • 36
    • 1
    克隆类型
    • 95
    • 44
    多克隆
    标记
    • 70
    • 18
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
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    • 2
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    • 2
    This AGT antibody is un-conjugated
    应用范围
    • 108
    • 46
    • 34
    • 27
    • 27
    • 19
    • 14
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    • 9
    • 8
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Angiotensinogen(AGT) detection. Tested with WB, IHC-P in Mouse.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Angiotensinogen(AGT) detection. Tested with WB, IHC-P in Mouse.
    Gene Name: angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
    Protein Name: Angiotensinogen
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived mouse Angiotensinogen recombinant protein (Position: D25-A115). Mouse Angiotensinogen shares 62.2% and 87.9% amino acid (aa) sequence identity with human and rat Angiotensinogen, respectively.
    亚型
    IgG
    Top Product
    Discover our top product AGT Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse , Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    别名
    AGT (AGT 产品)
    别名
    ANHU antibody, SERPINA8 antibody, AI265500 antibody, AngI antibody, AngII antibody, Aogen antibody, Serpina8 antibody, ANRT antibody, Ang antibody, PAT antibody, wu:fb62f06 antibody, wu:fj87b02 antibody, zgc:111892 antibody, AGT antibody, angt antibody, ANGT antibody, angiotensinogen antibody, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody, AGT antibody, Agt antibody, agt antibody
    背景
    AGT(ANGIOTENSINOGEN), also called SERPINA8, is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

    Synonyms: AGT | Angiotensin I | Angiotensin II | Angiotensin III | Angiotensin-1 | Angiotensin-2 | Angiotensin-3 | Angiotensinogen | ANGT | ANHU | P01019 | Pre angiotensinogen | Serpin A8 | SERPINA8
    基因ID
    183
    UniProt
    P11859
    途径
    JAK/STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
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